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For Biology Students

Punnett Square Maker Punnett Squares

Create professional Punnett squares for genetics problems instantly. Describe the cross, and AI generates a labeled diagram with genotype and phenotype ratios.

Monohybrid & DihybridGenotype RatiosPhenotype PredictionsPublication-Ready

Punnett Square Maker

Describe your Punnett square
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Your Punnett square will appear here

Describe the genetic cross and click Generate

Genetics Diagram Examples

Browse genetics diagram examples or generate your own above

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Autosomal Dominant Inheritance

Autosomal dominant pedigree paired with Punnett square predictions.

geneticsdominantinheritance

Autosomal Recessive Carrier Cross

Carrier cross Punnett square showing 25% affected probability.

geneticsrecessivecarrier

Sickle Cell Trait Cross

Sickle cell trait Punnett square for genetic counseling illustration.

sickle-cellmedicalgenetics

X-Linked Inheritance

X-linked recessive Punnett square showing carrier mother cross.

x-linkedsex-linkedgenetics

Genetics Symbols Reference

Genetics notation reference with Punnett square conventions.

referencesymbolsnotation

Dihybrid Cross Diagram

Dihybrid cross Punnett square showing the classic 9:3:3:1 ratio.

dihybridmendelianadvanced

What is a Punnett Square?

A Punnett square is a grid used in genetics to predict the genotype and phenotype ratios of offspring from a specific cross between two parents. Each cell in the grid represents a possible allele combination. Punnett squares are named after Reginald Punnett and remain the standard teaching tool for Mendelian inheritance in biology courses worldwide.

Types of Punnett Square Crosses

  • Monohybrid cross (2×2 grid) — predicts inheritance of one gene with two alleles
  • Dihybrid cross (4×4 grid) — predicts inheritance of two genes simultaneously
  • Test cross — crosses with a homozygous recessive to determine unknown genotype
  • Incomplete dominance cross — heterozygote shows blended phenotype (1:2:1 ratio)
  • Codominance cross — both alleles fully expressed in heterozygote (e.g., blood type)
  • X-linked cross — accounts for sex-linked inheritance on the X chromosome

How to Use a Punnett Square

Identify the parent genotypes, then place one parent's alleles across the top and the other's down the left side. Fill each cell by combining the column and row alleles. Count the resulting genotypes to determine ratios. For a standard monohybrid cross between two heterozygotes (Aa × Aa), you get a 1:2:1 genotype ratio and 3:1 phenotype ratio.

Applications in Genetics

Punnett squares are used in genetic counseling to calculate the probability of offspring inheriting specific conditions. They help plant and animal breeders predict trait distributions. In education, they make abstract probability concepts concrete and visual. Combined with pedigree charts, they allow researchers to trace inheritance patterns across generations.

Frequently Asked Questions

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